Insulin Potentiation Therapy (IPT) in New York

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What is IPT?

Insulin Potentiation Therapy (IPT) is a cancer treatment that uses insulin to enhance the power of traditional chemotherapy. Because cancer cells have more insulin receptors in their cell walls, they are more sensitive to insulin than normal cells. Insulin in small doses should open up the channels in the walls of cancer cells to let chemotherapeutic drugs more easily. That way, the chemotherapy doses can be lessened to about a tenth of the usual dose. 

It?s like going to a school where no one speaks your language, students are completely apathetic and everyone is at a different skill level. You would have to study much harder and do more homework in order to learn. Going to a school where the language is familiar, the courses are planned, and the students all want to learn will make it ten times easier to learn? just like using insulin to open up the cancer cells so that a higher concentration of the chemotherapy drugs can seep into the cells.

How does IPT Work?

Insulin is given through an IV after the patient has fasted for 6-8 hours. Shortly after, chemotherapy drugs are applied in a small dose. This way, the level of toxic drugs that the body must manage with is not nearly as noxious as the normal level. Since the insulin lowers the blood sugar, the chemotherapy drugs can take effect and an insulin solution with more sugar is implemented.  Insulin doses and sugar content will be specific to each patient. Treatment is usually given two times a week for three to five months.  Chemotherapy drugs can be taken in between sessions if necessary.

The History of IPT

Insulin Potentiation Therapy was invented in 1930 by the Mexican Doctor Donato Perez Garcia, Sr. (1). He realized that insulin could help treat viral diseases like polio, multiple sclerosis, ulcers, HIV, and chronic infections. His son, and later, grandson joined the family practice and they started honing in more on IPT for the treatment of cancer. In 1980?s this innovative approach to cancer started gaining support in the United States by M.D. Anderson and Dr. Steven G. Ayre. It is now widely used by holistic and alternative practices, although not as often with conventional practices.

When to Consider IPT

If you cannot tolerate conventional chemotherapy or you do not want it then you may consider Insulin Potentiation Therapy. It might help to achieve less of the harsh side effects of chemotherapy drugs while still delivering the drugs to their targets. 

Evidence for IPT

The effectiveness of Insulin Potentiation Therapy is supported by individual reports and small studies, but not yet by large or mainstream studies. For instance, a Georgetown University study in 1990?s showed that methotrexate, a common chemo drug, could invade cancer cells 10,000 times better when insulin was used to prepare the cells. Another study from Uruguay used 30 women with breast cancer who were against conventional therapy. Ten of the women took the drug methotrexate, ten took insulin, and ten others used both forms of medication, completing the IPT. After just eight weeks of treatment, women in the IPT group had less increase of tumor size compared to the women in the other two groups (2).

Another study concluded this, ?Our present experience with IPTLD (in more than 400 treated patients) with various tumors as well as the practical experience of the growing number of doctors practicing the method gives us a reason to assume that IPTLD method provides a real opportunity for resolving one of the most serious problems of toxicity associated with chemotherapy using maximum tolerated doses. A certain advantage of the method along with its effectiveness is the significantly improved quality of life of the treated patients? (3).

Risks of IPT

As with any medical treatment, IPT has its risks and benefits. Risks of IPT are mainly related to low sugar levels from the insulin. Since all patients respond to insulin differently, we monitor the levels carefully? blood sugar has the potential to quickly drop to dangerously low levels during IPT. If patients are already taking diabetes medication to lower blood sugar, then they may react even more severely to the IPT insulin.  

IPT shouldn?t be used in combination with some other medications. We will do a full exam before administering any treatments.


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